Fractional Flow Reserve Derived from Computer Tomography in Asymptomatic Patients with Type 2 Diabetes and Albuminuria without Significant Coronary Artery Stenosis—A Surrogate for Coronary Microvascular Dysfunction?
نویسندگان
چکیده
Background: Type 2 diabetes mellitus (T2D) patients with albuminuria have coronary microvascular dysfunction (CMD). Fractional flow reserve assessed by computed tomography angiography (FFRct) is dependent on the structure and function of microcirculation likely influenced CMD. We aimed to evaluate if asymptomatic T2D who had no significant artery stenosis but been diagnosed lower value nadir FFRct compared albuminuria. Methods results: This was a cross-sectional study which mean values in arteries symptoms angina. The were divided into two groups (albuminuria albuminuria) being defined as albumin–creatinine-ratio (ACR) ≥30 milligram per gram. between for left anterior descendent (FFRct-LAD), circumflex (FFRct-CX), right (FFRct-RCA) using two-sample Wilcoxon rank-sum (Mann–Whitney) test. Ninety-eight without 26 included. No differences detected FFRct-CX 0.86 ± 0.07 0.88 0.0, FFRct-RCA 0.05 0.07, or FFRct-LAD 0.82 albuminuria, respectively. Conclusion: In this observational study, we did not find that affected Therefore, it surrogate
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ژورنال
عنوان ژورنال: Hearts
سال: 2021
ISSN: ['2673-3846']
DOI: https://doi.org/10.3390/hearts2030029